ASPIRATE MORPHOLOGY Smears of the aspirate are placed in slides that are then viewed under the microscope. Number and type of cells are counted using the naked eye. |
CG/FISH FISH is the short name for a test called Fluorescence in situ hybridisation. It is a specific type of genetic test that looks for genetic abnormalities in the plasma cells found in bone marrow. |
FLOW CYTOMETRY Cells are tagged by means of laser technology and then machine counted. Far more cells can be counted and typed in this way than by aspirate morphology and more accurate percentages of cell types can be identified. |
GENE VARIANT SCREENING Presumably a molecular DNA test is performed on the samples in order to identify the genetic makeup of the leukaemia cells. |
HISTOPATHOLOGY Histopathology is the diagnosis and study of diseases of the tissues, and involves examining tissues and/or cells under a microscope. Histopathologists are responsible for making tissue diagnoses and helping clinicians manage a patient’s care. In a bone marrow context, histopathology is the microscopic analysis of trephine samples, and is the equivalent to the aspirate morphology actiuvity performed on the aspirate. |
MOLECULAR The body is simulated at a molecular level and interactions are observed in order to identify specific genetic mutations. |
PERIPHERAL BLOOD Key measures from the full blood counts are taken from the blood produced by the bone marrow whose samples were analysed in this report. This provides a sense of the health of the blood being produced by the bone marrow at this point in time. |
Sections of a bone marrow report |
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